
The bigger challenge may be covert, only showing its face after the development of a vaccine, whereas another challenge may be more overt and be easily identified. An example of an easily identifiable overt challenge faces the development of an HIV vaccination for Africans in the Sub-Saharan. The challenge to biomedical engineers and scientists would be to develop a vaccine in which the immunogens won't denature in warm weather or to develop a protective method for transporting the vaccine during a hot day. This is only one example ,however, there may be numerous other challenges regarding vaccination methods when applied in massive populations. For these reasons it is becoming increasingly more apparent that scientists developing not only vaccines, but also drugs and therapies, while working in concert with biomedical engineers and global health officials so that they may coordinate effective health technologies and strategies for addressing global health issues.